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KMID : 1098420050130040194
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Korean Journal of Medicinal Crop Science
2005 Volume.13 No. 4 p.194 ~ p.198
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Antioxidative Compounds in Extracts of Eleutherococcus senticosus Max. Plantlets
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Kim Myong-Jo
Kwon Yong-Soo
Yu Chang-Yeon
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Abstract
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Two antioxidative compounds were isolated from the methanolic extract of Eleutherococcus senticosus Max. plantlets and identified as chlorogenic acid and 1,4-di-o-caffeoyl-quinic acid on the basis of mass spectroscopy, ^1H-NMR and ^{13}C-NMR data. The DPPH free radical scavenging activities of chlorogenic acid (RC_{50};:;1.2;{mu}g) and 1,4-di-o-caffeoyl-quinic acid (RC_{50};:;0.4;{mu}g) were more effective than those of {alpha}-tocopherol;(RC_{50};:;12;{mu}g). Of them, 1,4-di-o-caffeoyl-quinic acid compound were isolated for the first time from this plant.
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KEYWORD
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Chlorogenic acid, 1, 4-di-o-caffeoyl-quinic acid, Eleutherococcus senticosus Max. DPPH free radical scavenging activity
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